brainpy.channels.ICaT_HP1992#

class brainpy.channels.ICaT_HP1992(size, keep_size=False, T=36.0, T_base_p=5.0, T_base_q=3.0, g_max=1.75, V_sh=- 3.0, phi_p=None, phi_q=None, method='exp_auto', name=None, mode=None)[source]#

The low-threshold T-type calcium current model for thalamic reticular nucleus proposed by (Huguenard & Prince, 1992) 1.

The dynamics of the low-threshold T-type calcium current model in thalamic reticular nucleus neurons 1 is given by:

\[\begin{split}I_{CaT} &= g_{max} p^2 q(V-E_{Ca}) \\ {dp \over dt} &= {\phi_p \cdot (p_{\infty}-p)\over \tau_p} \\ &p_{\infty} = {1 \over 1+\exp [-(V+52-V_{sh}) / 7.4]} \\ &\tau_{p} = 3+{1 \over \exp [(V+27-V_{sh}) / 10]+\exp [-(V+102-V_{sh}) / 15]} \\ {dq \over dt} &= {\phi_q \cdot (q_{\infty}-q) \over \tau_q} \\ &q_{\infty} = {1 \over 1+\exp [(V+80-V_{sh}) / 5]} \\ & \tau_q = 85+ {1 \over \exp [(V+48-V_{sh}) / 4]+\exp [-(V+407-V_{sh}) / 50]}\end{split}\]

where \(\phi_p = 5^{\frac{T-24}{10}}\) and \(\phi_q = 3^{\frac{T-24}{10}}\) are temperature-dependent factors (\(T\) is the temperature in Celsius), \(E_{Ca}\) is the reversal potential of Calcium channel.

Parameters

  • T (float, ArrayType) – The temperature.

  • T_base_p (float, ArrayType) – The brainpy_object temperature factor of \(p\) channel.

  • T_base_q (float, ArrayType) – The brainpy_object temperature factor of \(q\) channel.

  • g_max (float, ArrayType, Callable, Initializer) – The maximum conductance.

  • V_sh (float, ArrayType, Callable, Initializer) – The membrane potential shift.

  • phi_p (optional, float, ArrayType, Callable, Initializer) – The temperature factor for channel \(p\).

  • phi_q (optional, float, ArrayType, Callable, Initializer) – The temperature factor for channel \(q\).

References

1(1,2)

Huguenard JR, Prince DA (1992) A novel T-type current underlies prolonged Ca2+- dependent burst firing in GABAergic neurons of rat thalamic reticular nucleus. J Neurosci 12: 3804–3817.

See also

ICa_p2q_form

__init__(size, keep_size=False, T=36.0, T_base_p=5.0, T_base_q=3.0, g_max=1.75, V_sh=- 3.0, phi_p=None, phi_q=None, method='exp_auto', name=None, mode=None)[source]#

Methods

__init__(size[, keep_size, T, T_base_p, ...])

clear_input()

cpu()

Move all variable into the CPU device.

cuda()

Move all variables into the GPU device.

current(V, C_Ca, E_Ca)

dp(p, t, V)

dq(q, t, V)

f_p_inf(V)

f_p_tau(V)

f_q_inf(V)

f_q_tau(V)

get_delay_data(identifier, delay_step, *indices)

Get delay data according to the provided delay steps.

load_state_dict(state_dict[, warn])

Copy parameters and buffers from state_dict into this module and its descendants.

load_states(filename[, verbose])

Load the model states.

nodes([method, level, include_self])

Collect all children nodes.

offline_fit(target, fit_record)

offline_init()

online_fit(target, fit_record)

online_init()

register_delay(identifier, delay_step, ...)

Register delay variable.

register_implicit_nodes(*nodes[, node_cls])

register_implicit_vars(*variables, ...)

reset(V, C_Ca, E_Ca[, batch_size])

Reset function which reset the whole variables in the model.

reset_local_delays([nodes])

Reset local delay variables.

reset_state(V, C_Ca, E_Ca[, batch_size])

Reset function which reset the states in the model.

save_states(filename[, variables])

Save the model states.

state_dict()

Returns a dictionary containing a whole state of the module.

to(device)

Moves all variables into the given device.

tpu()

Move all variables into the TPU device.

train_vars([method, level, include_self])

The shortcut for retrieving all trainable variables.

tree_flatten()

Flattens the object as a PyTree.

tree_unflatten(aux, dynamic_values)

New in version 2.3.1.

unique_name([name, type_])

Get the unique name for this object.

update(tdi, V, C_Ca, E_Ca)

The function to specify the updating rule.

update_local_delays([nodes])

Update local delay variables.

vars([method, level, include_self, ...])

Collect all variables in this node and the children nodes.

Attributes

global_delay_data

Global delay data, which stores the delay variables and corresponding delay targets.

mode

Mode of the model, which is useful to control the multiple behaviors of the model.

name

Name of the model.

varshape