ICaHT_HM1992

ICaHT_HM1992#

class brainpy.dyn.ICaHT_HM1992(size, keep_size=False, T=36.0, T_base_p=3.55, T_base_q=3.0, g_max=2.0, V_sh=25.0, method='exp_auto', name=None, mode=None)[source]#

The high-threshold T-type calcium current model proposed by (Huguenard & McCormick, 1992) [1].

The high-threshold T-type calcium current model is adopted from [1]. Its dynamics is given by

\[\begin{split}\begin{aligned} I_{\mathrm{Ca/HT}} &= g_{\mathrm{max}} p^2 q (V-E_{Ca}) \\ {dp \over dt} &= {\phi_{p} \cdot (p_{\infty} - p) \over \tau_{p}} \\ &\tau_{p} =\frac{1}{\exp \left(\frac{V+132-V_{sh}}{-16.7}\right)+\exp \left(\frac{V+16.8-V_{sh}}{18.2}\right)}+0.612 \\ & p_{\infty} = {1 \over 1+exp[-(V+59-V_{sh}) / 6.2]} \\ {dq \over dt} &= {\phi_{q} \cdot (q_{\infty} - h) \over \tau_{q}} \\ & \begin{array}{l} \tau_q = \exp \left(\frac{V+467-V_{sh}}{66.6}\right) \quad V< (-80 +V_{sh})\, mV \\ \tau_q = \exp \left(\frac{V+22-V_{sh}}{-10.5}\right)+28 \quad V \geq (-80 + V_{sh})\, mV \end{array} \\ &q_{\infty} = {1 \over 1+exp[(V+83 -V_{shift})/4]} \end{aligned}\end{split}\]

where \(phi_p = 3.55^{\frac{T-24}{10}}\) and \(phi_q = 3^{\frac{T-24}{10}}\) are temperature-dependent factors (\(T\) is the temperature in Celsius), \(E_{Ca}\) is the reversal potential of Calcium channel.

Parameters:
  • T (float, ArrayType) – The temperature.

  • T_base_p (float, ArrayType) – The brainpy_object temperature factor of \(p\) channel.

  • T_base_q (float, ArrayType) – The brainpy_object temperature factor of \(q\) channel.

  • g_max (float, ArrayType, Initializer, Callable) – The maximum conductance.

  • V_sh (float, ArrayType, Initializer, Callable) – The membrane potential shift.

References

See also

ICa_p2q_form

master_type#

alias of Calcium