ICaL_IS2008#
- class brainpy.dyn.ICaL_IS2008(size, keep_size=False, T=36.0, T_base_p=3.55, T_base_q=3.0, g_max=1.0, V_sh=0.0, method='exp_auto', name=None, mode=None)[source]#
The L-type calcium channel model proposed by (Inoue & Strowbridge, 2008) [1].
The L-type calcium channel model is adopted from (Inoue, et, al., 2008) [1]. Its dynamics is given by:
\[\begin{split}I_{CaL} &= g_{max} p^2 q(V-E_{Ca}) \\ {dp \over dt} &= {\phi_p \cdot (p_{\infty}-p)\over \tau_p} \\ & p_{\infty} = {1 \over 1+\exp [-(V+10-V_{sh}) / 4.]} \\ & \tau_{p} = 0.4+{0.7 \over \exp [(V+5-V_{sh}) / 15]+\exp [-(V+5-V_{sh}) / 15]} \\ {dq \over dt} &= {\phi_q \cdot (q_{\infty}-q) \over \tau_q} \\ & q_{\infty} = {1 \over 1+\exp [(V+25-V_{sh}) / 2]} \\ & \tau_q = 300 + {100 \over \exp [(V+40-V_{sh}) / 9.5]+\exp [-(V+40-V_{sh}) / 9.5]}\end{split}\]where \(phi_p = 3.55^{\frac{T-24}{10}}\) and \(phi_q = 3^{\frac{T-24}{10}}\) are temperature-dependent factors (\(T\) is the temperature in Celsius), \(E_{Ca}\) is the reversal potential of Calcium channel.
- Parameters:
References
See also
ICa_p2q_form