ICaN_IS2008

ICaN_IS2008#

class brainpy.dyn.ICaN_IS2008(size, keep_size=False, E=10.0, g_max=1.0, phi=1.0, method='exp_auto', name=None, mode=None)[source]#

The calcium-activated non-selective cation channel model proposed by (Inoue & Strowbridge, 2008) [2].

The dynamics of the calcium-activated non-selective cation channel model [1] [2] is given by:

\[\begin{split}\begin{aligned} I_{CAN} &=g_{\mathrm{max}} M\left([Ca^{2+}]_{i}\right) p \left(V-E\right)\\ &M\left([Ca^{2+}]_{i}\right) ={[Ca^{2+}]_{i} \over 0.2+[Ca^{2+}]_{i}} \\ &{dp \over dt} = {\phi \cdot (p_{\infty}-p)\over \tau_p} \\ &p_{\infty} = {1.0 \over 1 + \exp(-(V + 43) / 5.2)} \\ &\tau_{p} = {2.7 \over \exp(-(V + 55) / 15) + \exp((V + 55) / 15)} + 1.6 \end{aligned}\end{split}\]

where \(\phi\) is the temperature factor.

Parameters:
  • g_max (float) – The maximal conductance density (\(mS/cm^2\)).

  • E (float) – The reversal potential (mV).

  • phi (float) – The temperature factor.

References

master_type#

alias of CalciumDyna